RiteMED Clonidine Adverse Reactions

Cardiovascular: Atrioventricular block, bradyarrhythmia, bradycardia, chest pain, congestive heart failure, ECG abnormalities (e.g., arrhythmias, sinus node arrest, junctional bradycardia, conduction disturbances such as high degree atrioventricular block) manifested as Wenckebach period or ventricular trigeminy, flushes, hypotension, increases in blood pressure, orthostatic symptoms, palpitations, Raynaud's phenomenon, sinus bradycardia, syncope, tachycardia.
Dermatologic: Alopecia, hair thinning, angioedema, hives, pruritus, rash, urticaria.
Gastrointestinal: Abdominal pain, anorexia, constipation, dry mouth, nausea, parotitis, pseudo-obstruction (including colonic pseudo-obstruction), salivary gland pain, vomiting.
Genitourinary: Decreased sexual activity, difficulty in micturition, erectile dysfunction, impotence, loss of libido, nocturia, urinary retention.
Hematologic: Thrombocytopenia.
Hepatic: Hepatitis, mild transient abnormalities in liver function tests.
Metabolic: Gynecomastia, transient elevation of blood glucose and serum creatine phosphokinase, transient hyperglycemia, weight gain.
Musculoskeletal: Cramps of the lower limbs, fatigue, malaise, muscle or joint pain, weakness.
Nervous: Agitation, anxiety, behavioral changes, cerebrovascular accidents, confusion, delirium, delusional perception, depression, dizziness, drowsiness, hallucinations (including visual and auditory), headache, insomnia, irritability, lethargy, localized numbness, mental depression, nervousness, nightmares, paresthesia, restlessness, sedation, sleep disorder, vivid dreams.
Other adverse effects: Accommodation disorder; blurred vision; decreased lacrimation; dryness, itching or burning of eyes; dryness of the nasal mucosa; fever; increased sensitivity to alcohol; pallor; weakly positive Coombs' test; withdrawal syndrome.